76ers vs Bucks Prediction, Odds & Game Preview 4/3/2025

The Philadelphia 76ers will look to snap their nine-game losing streak when they host the Milwaukee Bucks at Wells Fargo Center Thursday night, but they'll need to overcome both Giannis Antetokounmpo's scorching form and their own depleted roster to have any chance.

With the Greek superstar dropping 37 points in Milwaukee's last outing while shooting a blistering 68.9% from the field against Phoenix, the Sixers' league-worst defensive metrics (ranking 30th in opponent shooting percentage) could spell disaster for the home squad.

The injury-ravaged Philadelphia 76ers vs Milwaukee Bucks matchup threatens to become one-sided as the home team limps into the contest without stars Maxey, Embiid, and George while the away team aims for their eighth straight victory in this increasingly lopsided rivalry.

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Philadelphia 76ers vs. Milwaukee Bucks preview

The struggling 76ers have essentially thrown in the towel on their season as they limp into Thursday's clash with the Bucks at Wells Fargo Center missing practically their entire starting lineup – Embiid, Maxey, George, and Oubre are all sidelined.

Milwaukee comes in looking to build on their impressive shooting display against Phoenix where they hit a blistering 68.9% from the field, led by Giannis Antetokounmpo's 37-point masterclass.

Despite posting a mediocre 4-6 record over their last ten games, the Bucks have dominated this matchup historically, winning seven straight against Philadelphia including all three meetings this season.

The stark contrast in these teams' current states couldn't be more evident – Milwaukee fighting to hold their sixth seed in the East while Philly has dropped 24 of their last 27 games in what's become a lost cause.

Quentin Grimes showed some fight with 26 points in the Sixers' recent loss to New York, but Philadelphia's league-worst 26-50 record against the spread tells you everything about their competitive level lately.

The Bucks' defensive vulnerability on the road (four games below .500 away from home) might offer a sliver of hope for a 76ers squad that ranks dead last in fourth-quarter win percentage this season.

Look for Kyle Kuzma and Brook Lopez to exploit Philadelphia's porous defense which has surrendered over 120 points per game during their current nine-game skid.

Without Damian Lillard, Milwaukee will lean even harder on Giannis to dominate a Sixers team fielding what barely qualifies as an NBA roster at this point.