76ers vs Timberwolves Prediction, Odds & Game Preview 4/5/2025

The scorching-hot Minnesota Timberwolves bring their four-game winning streak to Philadelphia, where they'll face a decimated 76ers squad that's dropped 10 straight and is playing purely for pride at this point.

This interconference matchup features Anthony Edwards, fresh off a 28-point performance against Brooklyn, leading Minnesota's playoff push against a Sixers team missing its entire star trio of Embiid, Maxey, and George.

All signs point to a mismatch when the hobbled home team 76ers host the away team Timberwolves, who are locked in a fierce battle for the West's final guaranteed playoff spot.

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Philadelphia 76ers vs. Minnesota Timberwolves preview

The Timberwolves are riding a red-hot four-game winning streak into Philadelphia, where they'll face a 76ers squad that's simply trying to play out the string after dropping 10 straight contests and 13 of their last 14 games.

Minnesota's defense has been their calling card this season – ranking 6th in scoring defense at 109.4 points per game – while Anthony Edwards continues his breakout campaign averaging 27.3 points per contest.

The severely depleted 76ers, missing their entire star trio of Embiid, Maxey, and George for the remainder of the season, have been forced to rely on unexpected contributors like Adem Bona, who dropped 28 points in their last outing against Milwaukee.

What's particularly brutal for Philly fans is how their team has shown flashes – they built a 17-point lead against the Bucks before watching it evaporate, continuing a trend of defensive collapses that's seen them surrender 124.4 points per game over their last 10 contests.

The Wells Fargo Center has historically been a tough venue for Minnesota, with the 76ers winning eight of their last 10 home matchups against the Timberwolves.

But with Minnesota battling Memphis for the final guaranteed playoff spot in the crowded Western Conference, expect Edwards and company to attack a Philadelphia defense that's been leaking points like a sieve lately.

Julius Randle and Rudy Gobert provide Minnesota with a formidable frontcourt advantage against a depleted 76ers roster – Gobert's coming off a monster 21-point, 18-rebound performance against Brooklyn.

This interconference clash features teams heading in completely opposite directions – one desperately fighting for playoff positioning while the other is simply trying to find building blocks for next season's campaign.