Trail Blazers vs Spurs Prediction, Odds & Game Preview 4/6/2025

The Portland Trail Blazers welcome the San Antonio Spurs to Moda Center in a battle between two teams clinging to the mathematical possibility of postseason play despite long odds.

Both squads come in battling significant injury concerns – Portland potentially missing Simons, Avdija, and definitely without Ayton, while San Antonio continues to navigate life without their franchise cornerstone Wembanyama.

The matchup presents an interesting contrast between Chris Paul's veteran leadership for the visiting Spurs against the young firepower of Shaedon Sharpe's Blazers, who desperately need to snap their 0-3 season series drought against the Spurs to keep their faint playoff dreams alive.

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Portland Trail Blazers vs. San Antonio Spurs preview

The Spurs roll into Portland looking to complete a season sweep after winning all three previous matchups with the Blazers, though both teams are essentially playing for pride at this late stage of the season.

Victor Wembanyama's absence has thrust rookie Stephon Castle into the spotlight, with the youngster coming off an impressive 22-point performance that's giving Spurs fans something to cheer about during this rebuilding year.

Portland's injury woes continue to mount as DeAndre Ayton remains sidelined, while key scorers Anfernee Simons and Deni Avdija – fresh off a 37-point outburst against Chicago – are questionable, potentially leaving the Blazers severely short-handed.

Despite missing their franchise cornerstone, San Antonio's veteran presence in Chris Paul provides stability, while Devin Vassell (16.4 PPG) and Harrison Barnes have stepped up their scoring duties in recent games.

The Moda Center contest might lack playoff implications, but basketball purists should enjoy watching these young rosters battling it out – especially with Portland's exciting 21-year-old Shaedon Sharpe, who's quietly averaging 18.2 points this season.

Defense likely won't be the story here, with both squads ranking higher in offensive efficiency than defensive metrics, setting up what could be a surprisingly entertaining, high-scoring affair.

I've got a hunch that Castle might just put on another show for San Antonio, continuing his late-season emergence that's giving Spurs fans hope for next year's campaign.

While the Blazers have shown fight all season despite mounting injuries, the Spurs' slightly more cohesive lineup should give them an edge in what might end up being one of Sunday's most competitive matchups.