Major League Soccer takes center stage this weekend with two compelling matchups as Toronto FC hosts Minnesota United and Orlando City squares off against New York Red Bulls.

Our MLS best bets focus on these Saturday showdowns, offering prime opportunities for bettors looking to capitalize on the action available through MLS Season Pass and Bet365 globally.

Continue reading for our expert MLS picks and comprehensive analysis of these Eastern Conference clashes.

MLS betting tips

GameTimePick
Toronto logoMinnesota logo
2:30 PMMinnesota United to win (+135)
Orlando logoRed Bulls logo
4:30 PMBoth Teams to Score - Yes (-145)
Vancouver logoAustin logo
7:30 PMUnder 2.5 Total Goals (+115)

Toronto vs. Minnesota

Minnesota logo

Saturday, Apr 12

2:30 PM

BMO Field

Minnesota logo

Minnesota United heads into Toronto as slight favorites tonight, and I'm backing them to take all three points. The Loons have shown remarkable consistency on the road this season, grinding out results with disciplined defensive performances. Their counter-attacking style seems perfectly suited for away fixtures, where they can absorb pressure and strike quickly on the break.

Toronto FC has been struggling to find their footing at home this season. Their backline has shown concerning vulnerabilities, especially against teams that transition quickly from defense to attack. The absence of their defensive midfielder due to suspension creates a massive hole in the middle of the park that Minnesota's creative players should exploit.

When looking at recent form, Minnesota has picked up points in three of their last four road games - impressive in a league where away wins are notoriously difficult. Their attacking duo has developed a chemistry that's causing problems for even the most organized defenses, and Toronto's back four doesn't qualify as particularly organized right now.

The head-to-head record slightly favors Minnesota in recent meetings, with Toronto failing to beat them in their last three encounters. What really sells me on this pick is Minnesota's disciplined approach under their coach, who has implemented a pragmatic style that travels well in MLS.

Weather conditions in Toronto tonight should favor Minnesota's more direct approach, with forecasted rain making possession soccer difficult. The visitors have shown they can grind out results in adverse conditions, and I expect them to snatch a goal or two on the counter while limiting Toronto's effectiveness in the final third.

Toronto's home form simply hasn't been convincing enough to back them here. With Minnesota's organized defensive structure and efficient counter-attacking style, I'm confident they'll come away with all three points in what should be a tight but ultimately rewarding contest for the visitors.

Orlando vs. Red Bulls

Red Bulls logo

Saturday, Apr 12

4:30 PM

Inter&Co Stadium

Red Bulls logo

I'm taking Both Teams to Score in tonight's clash between Orlando City and New York Red Bulls, and honestly, this bet feels like printing money. Both sides have been leaking goals lately while showing plenty of firepower up front - the perfect recipe for a BTTS bet.

Orlando City's home games have been particularly entertaining this season, with their attack looking dangerous but their defense often falling apart at crucial moments. They've scored in every home game so far, but have kept just one clean sheet in their last seven matches overall. Their high-pressing style creates chances but also leaves gaps that the Red Bulls are perfectly positioned to exploit.

New York's approach under their manager remains as direct and aggressive as ever. Their infamous pressing system creates turnovers in dangerous areas, but also leaves them exposed when teams break that press. Four of their last five matches have ended with both teams finding the net, highlighting both their attacking threat and defensive vulnerabilities.

The history between these teams points strongly toward goals at both ends. Three of their last four meetings have ended with both teams scoring, with matches typically featuring high-intensity, end-to-end action. Neither side seems capable of shutting the other down completely.

Orlando's attacking trio has been in sparkling form at home, creating chances consistently and finishing clinically. Even against solid defenses, they find ways to break through, and the Red Bulls certainly don't qualify as a solid defense based on recent performances. On the flip side, New York's direct approach and set-piece threat should find joy against an Orlando backline that struggles with defending crosses.

With both managers likely to set up their teams to attack rather than contain, this has all the ingredients for an entertaining, goal-filled encounter. I'd be shocked if either team manages to keep a clean sheet, making BTTS one of the safest plays on today's MLS slate.

Vancouver vs. Austin

Austin logo

Saturday, Apr 12

7:30 PM

BC Place

Austin logo

I'm backing Under 2.5 goals in tonight's clash between Vancouver Whitecaps and Austin FC, though this one definitely flies under the radar on today's MLS slate. Both teams have shown a tendency toward low-scoring affairs, particularly when facing opponents with similar tactical setups.

Vancouver's home form has been built on defensive solidity rather than attacking flair. Their coach has implemented a pragmatic approach that prioritizes maintaining shape and limiting opposition chances over free-flowing attack. At home, they're content to win ugly rather than entertain, with four of their last six home matches featuring fewer than three goals.

Austin FC arrives in a defensive mindset, knowing that road points in MLS are precious. Their away strategy typically involves staying compact, frustrating the home team, and looking to nick a goal on the counter or from a set piece. This conservative approach has resulted in three of their last four away matches going under 2.5 goals.

The tactical matchup here screams deadlock. Vancouver lacks the creative spark to break down organized defenses, while Austin doesn't commit enough numbers forward on the road to create consistent danger. We're likely looking at a chess match where neither side takes excessive risks to break the deadlock.

Weather conditions in Vancouver tonight could further limit goalscoring opportunities, with rain in the forecast potentially slowing down the already methodical pace both teams prefer. Wet conditions typically favor defenders over attackers and lead to fewer clean striking opportunities.

Historical meetings between these sides have been tight affairs with goals at a premium. Their last three encounters averaged just 2.0 goals per match, with neither team able to dominate proceedings. Everything points toward another tactical, low-scoring affair that should comfortably stay under 2.5 goals.

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