Wednesday's Premier League slate offers a tantalizing mix of high-stakes matchups with Liverpool hosting Everton in a fiery Merseyside derby while Manchester City welcome Leicester City to the Etihad Stadium.
Our Premier League best bets highlight Crystal Palace's impressive form against struggling Southampton, Brighton's surprising edge over Champions League-chasing Aston Villa, and the goal-scoring prowess of standouts like Mohamed Salah and Alexander Isak.
Read on for our expert analysis and Premier League picks that deliver value across multiple markets including correct scores, anytime goalscorers, and both teams to score opportunities.
Premier League betting tips
Game | Time | Pick |
---|---|---|
![]() ![]() | 7:45 PM | Both Teams To Score & Over 2.5 Goals (8/11) |
![]() ![]() | 7:45 PM | Crystal Palace to Win (4/6) |
![]() ![]() | 8:00 PM | Both Teams To Score (21/20) |
Newcastle vs. Brentford

Wednesday, Apr 2
7:45 PM

The clash between Newcastle and Brentford at St. James' Park promises to be a goal-fest if recent form is anything to go by. Eddie Howe's Magpies have been absolutely electric in front of their home supporters, with their last seven Premier League matches on Tyneside all featuring over 2.5 goals. This attacking mindset was perfectly illustrated in their recent 4-3 thriller against Nottingham Forest where defensive solidity took a backseat to entertaining, front-foot football.
Brentford aren't exactly shy in front of goal either, particularly on their travels. Four of their last five away days have crossed the 2.5 goal threshold, with Thomas Frank's men finding the net with impressive regularity on the road. In fact, the Bees have only failed to score in three of their 19 away fixtures across all competitions this term – a testament to their attacking philosophy regardless of venue.
Looking at the head-to-head record provides even more evidence for goals. The last three competitive meetings between these sides have seen both teams find the net and the total goal count exceed 2.5. Most recently, Newcastle claimed a 4-2 victory over Brentford last May, and there's little reason to expect a more cautious approach from either side this time around.
Newcastle's home record this season further strengthens the case, with Howe's men scoring in 16 of their 18 home fixtures. The Magpies' attack, spearheaded by the in-form Alexander Isak, looks capable of breaching any defence, while their own backline has shown vulnerability that Brentford will surely look to exploit.
The return to fitness of key attacking players for both sides should ensure this bet lands comfortably. Newcastle's offensive capabilities are well-documented, but Brentford's counter-attacking threat shouldn't be underestimated. With both managers likely to set up their teams to play on the front foot, expect the net to bulge multiple times at St. James' Park in what promises to be an entertaining Wednesday night spectacle.
Southampton vs. Crystal Palace

Wednesday, Apr 2
7:45 PM

Crystal Palace head to St. Mary's as one of the form teams in the Premier League, having won seven of their last eight matches across all competitions under the astute guidance of Oliver Glasner. The Austrian manager has completely transformed Palace's fortunes since taking over, implementing a more progressive, attacking style that has seen them score goals for fun and climb the table impressively.
Southampton, by stark contrast, are enduring a nightmare run on home soil. The Saints have suffered defeat in a staggering 11 of their last 12 home fixtures across all competitions. This dismal record at St. Mary's has been a significant factor in their relegation struggle, with Russell Martin's side looking increasingly likely to make an immediate return to the Championship.
Palace's away form has been particularly impressive recently, with the Eagles showcasing their counter-attacking prowess on the road. They've netted two or more goals in seven of their last nine Premier League away days – a statistic that will strike fear into a Southampton defence that has looked extremely vulnerable, conceding multiple goals in eight of their last nine league games at St. Mary's.
The individual quality in this Palace squad is beginning to shine through under Glasner's management. Eberechi Eze and Michael Olise provide creativity in abundance, while Ismaila Sarr has been in red-hot form with four goals in his last four competitive outings. After netting against Fulham at the weekend, Sarr's confidence is sky-high and he'll fancy his chances against Southampton's leaky backline.
While Southampton have shown flashes of their attacking potential in recent weeks, scoring against quality opposition like Liverpool and Newcastle, their defensive frailties ultimately continue to undermine their efforts. Palace's newfound confidence, tactical cohesion, and superior quality across the pitch should prove too much for the struggling Saints, making the away win at odds of 4/6 a value proposition that's hard to ignore.
Liverpool vs. Everton

Wednesday, Apr 2
8:00 PM

The Merseyside derby between Liverpool and Everton at Anfield has all the ingredients for goals at both ends this Wednesday. The Reds might be in pole position in the title race, but their recent defensive record at home has been surprisingly leaky, with Jürgen Klopp's men conceding in six of their last seven Premier League home games. This vulnerability at the back gives Everton genuine hope of finding the net in what's always a highly-charged fixture.
Liverpool's confidence has taken something of a hit following their Champions League elimination at the hands of Atalanta and their EFL Cup final defeat. While they remain formidable, particularly at Anfield, there's been a slight defensive fragility creeping into their game that opponents have been able to exploit. The absence of Alisson through injury has certainly contributed to this, with Caoimhin Kelleher – despite his obvious quality – not quite providing the same commanding presence between the sticks.
Everton come into this derby in resurgent form under Sean Dyche. The Toffees have seen both teams score in each of their last six Premier League outings, highlighting their improved attacking output while acknowledging they're still not watertight at the back. Everton have found the net in each of their last three league fixtures, scoring exactly once on each occasion – a trend that suggests they have the firepower to trouble their local rivals.
Mohamed Salah continues to lead the way for Liverpool in both goals and assists in the Premier League this season, and the Egyptian has a particularly impressive record against Everton with eight goals in previous derbies. His nine goals and four assists in his last eight Premier League appearances underscore just how difficult he is to contain, meaning Everton will almost certainly concede, but they have the attacking weapons to respond.
The historical intensity of the Merseyside derby adds another dimension that often leads to open, emotional encounters where tactical discipline can sometimes go out the window. With Liverpool pushing for the title and Everton fighting to ensure Premier League survival, both sides have plenty to play for beyond just local bragging rights. All things considered, backing both teams to find the net looks the shrewd play in what promises to be another memorable chapter in this fierce rivalry.
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